The xone DX is ok, but the jogwheels are absolutely useless and it’s a little outdated.
As far as ITCH samples are concerned, it has the same SP-6 sample player that scratch live has but none of the current ITCH controllers have buttons mapped for it (including the twitch), so it’s only useable with the keyboard. They’ve said that midi mapping for external controllers is on its way though (ie you could use a kontrol X1 or something).
Personally I’d go for the S4 if you’re set on having 4 channels, or check out the new Vestax VCI-400.