The best thing you can do is practise and experiment. Like with any instrument it’s going to take time and patience, plus Skrillex has a lot of money from his dubstep career and the days when he was in From First to Last so he can afford the real high-end gear. Also, pretty much every veteran musician is still learning new tricks even after 40 years of playing.
I looked up online how to do bass drops recently and from what I’ve gathered it’s a case of using the high, middle and low knobs on the mixer along with pitch changes and if available various modulation and FX pedals.
When it comes to music though, I’m a firm believer in having your own sound and style. It’s okay to copy and be influenced by a musician but if we all copied our favourite musicians we’d all just be reproductions of that musician, whether they be a guitarist, drummer or trance mixer.