Without knowing what VDJ offers, I know echo on 1/2-1/4 is a great way to fade out with some creative EQing and filters. This however varies massively on the genre I think, and that would also change how you mix. Its harder to beatmix rock for an example, whereas it would not necessarily make a lot of sense to do hard and fast cuts in techno mixes. Not all transitions need effects.
If you’re newish to DJing or with your system at least, try just messing around a bit and seeing what works best for you. There are a ton of ways to mix songs together creatively and that’s what makes DJing so much fun 🙂