What Ricky Said!
Plan your opener, If i’m playing for an hour ill usually plan, and have it timed my first 15 minutes, in them 15 minutes ill play a few different sub genres(mainly drum and bass i play so jump up, big room, liquid) and see what people like the most and go down that route!
Dont be scared to think, this isnt working lets change it up! If it aint working, change it, but also dont change it straight away give people time to get into your groove your work flow, and with this, dont expect anyone and everyone to dance from start to finish of your set!
Finally, look at your body language behind the decks, stand up tall, look confident and enjoy your self.