It’s up to how creative and adventurous you are feeling. I am old school and I get squirmish if we go more than 3-4 bpm up or down.
There are some technical limitations, like the amount of work the CPU has to do as the difference becomes bigger is increasing (a lot). At some point there can be audible artifacts from the key-lock processing happening.
And then there is the “feeling” of a track. Especially well-known tracks. I always feel something is “off” when the speed difference becomes to big. So I always fear the audience could be feeling the same.
Again, if it fits some creative urge, go with it. It may just work out. I’ll stick to my 3-4 bpm though. Anything more than that is needed? There are few other tricks than straight beatmatching we have in our toolbox, right?
Greetinx.